Uncommon Fibroinflammatory Sinonasal Tract Lesions: Granulomatosis with Polyangiitis, Eosinophilic Angiocentric Fibrosis, and Rosai–Dorfman Disease

Thompson LDR.
Surg Pathol Clin. 2024 Dec;17(4):549-560. doi: 10.1016/j.path.2024.07.007. Epub 2024 Aug 16.
Fibroinflammatory lesions of the sinonasal tract include inflammatory polyps (chronic rhinosinusitis), various infious sarcoidosis, and NK/T-cell lymphoma as examples of the most commonly encountered lesions. However, the differential diagnosis includes several less frequently encountered entities, such as granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiits (Churg-Strauss), eosinophilic angiocentric fibrosis considered part of IgG4-related disease, and Rosai-Dorfman disease. This review focuses on these latter entities providing an update on clinical, laboratory, imaging, histology, and ancillary testing employed to reach an actionable
diagnosis.
PubMed ID: 39489548
Article Size: 8 MB