Data Set for the Reporting of Pheochromocytoma and Paraganglioma: Explanations and Recommendations of the Guidelines from the International Collaboration on Cancer Reporting (ICCR).

Head & Neck, Staging
Thompson LDR, Gill AJ, Asa SL, Clifton-Bligh RJ, de Krijger RR, Kimura N, Komminoth P, Lack EE, Lenders JWM, Lloyd RV, Papathomas TG, Sadow PM, Tischler AS.
Hum Pathol. 2021 Apr;110:83-97. doi: 10.1016/j.humpath.2020.04.012. Epub 2020 May 11.
SUMMARY BACKGROUND AND OBJECTIVES: The International Collaboration on Cancer Reporting (ICCR) is a not-for-profit to develop evidence-based, internationally agreed-upon standardized data sets for each anatomic site, to be used throughout the world. Providing global standardization of pathology tumor classification, staging, and other reporting elements will lead to improved patient management and enhanced epidemiological research.
METHODS: Pheochromocytoma and paraganglioma are uncommon and are frequently overlooked in registry data sets. Malignant criteria have previously been defined only when there was metastatic disease.
RESULTS: With recent recognition of a significant inheritance association and the development of risk stratification tools, this data set was created in order to obtain more meaningful outcomes and management data, using similar criteria across the global pathology community. Issues related to key core and non-core elements, especially clinical hormonal status, familial history, tumor focality, proliferative fraction, adverse or risk stratification features, and ancillary techniques, are discussed in the context of daily application to these types of specimens.
CONCLUSIONS: The ICCR data set, developed by an international panel of endocrine organ specialists, establishes a pathology-standardized reporting guide for pheochromocytoma and paraganglioma.
PubMed ID: 32407815
Article Size: 7 MB

Meaningful Value Added by Standardized, Internationally Validated, and Evidence-Based Pathology Data Sets for Cancer Reporting of Head and Neck Sites Coordinated by the International Collaboration on Cancer Reporting.

Staging
Thompson LDR.
Arch Pathol Lab Med. 2019 Apr;143(4):422-423. doi: 10.5858/arpa.2018-0489-ED.
This is an introduction to the Special Section–Structured Reporting Data Sets for Head and Neck Tumors From the International Collaboration on Cancer Reporting, Part I
PubMed ID: 30920861
Article Size: <1 MB

Carcinomas of the Hypopharynx, Larynx and Trachea (TNM8)

Head & Neck, Staging
Helliwell T, Chernock R, Dahlstrom JE, Gale N, McHugh J, Perez-Ordonez B, Roland N, Zidar N, Thompson LDR.
(2018) Carcinomas of the Hypopharynx, Larynx and Trachea, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-17-0

SCOPE:

The dataset has been developed for the reporting of resection and biopsy specimens of mucosal malignancies of the larynx, hypopharynx and trachea. The protocol applies to all invasive carcinomas of the larynx, hypopharynx and trachea (including the supraglottis, glottis, and subglottis). Salivary-type malignancies arising from mucosal glands of the hypopharynx and larynx should be recorded in this dataset. Mucosal melanoma is presented in a separate dataset. Lymphomas and sarcomas are not included. Malignancies arising at other sites in the head and neck region, and neck dissections and nodal excisions are dealt with in separate datasets which may be used, as appropriate, in conjunction with this dataset. Where more than one anatomically or histologically distinct primary tumours occur, a separate dataset should be completed for each tumour.

EXPERT COMMITTEE:
* Chair – Tim Helliwell, UK
* Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* Rebecca Chernock, USA
* Jane Dahlstrom, Australia
* Nina Gale, Slovenia
* Jonathan McHugh, USA
* Bayardo Perez-Ordonez, Canada
* Nick Roland, UK
* Nina Zidar, Slovenia
ISBN: 978-1-925687-17-0
Article Size: 1.5 MB
 
Helliwell T, Chernock R, Dahlstrom JE, Gale N, McHugh J, Perez-Ordonez B, Roland N, Zidar N, Thompson LDR.
Arch Pathol Lab Med. 2019 Apr;143(4):432-438. doi: 10.5858/arpa.2018-0419-SA. Epub 2018 Nov 30.
PubMed ID: 30500292
Article Size: 2 MB

Carcinomas of the Major Salivary Glands (TNM8)

Head & Neck, Staging
Seethala RR, Altemani A, Ferris RL, Fonseca I, Gnepp DR, Ha P, Nagao T, Skalova A, Stenman G, Thompson LDR.
(2018) Carcinomas of the Major Salivary Glands, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-21-7

SCOPE:

The dataset has been developed for the reporting of resection and biopsy specimens of malignant neoplasms and associated carcinoma in situ arising from the major salivary glands. The protocol applies to all carcinomas of the parotid, submandibular and sublingual glands. Melanomas, lymphomas, and sarcomas are dealt with in separate datasets. Minor salivary gland malignancies arising in the oral cavity, nasal cavity and paranasal sinuses, trachea, nasopharynx, oropharynx and hypopharynx and odontogenic specimens are staged according to their anatomical sub-site and are dealt with in separate datasets. In addition, neck dissections and nodal excisions are dealt with in a separate dataset, and this dataset should be used in conjunction, where applicable. For bilateral tumours, a separate dataset should be completed for each tumour.

EXPERT COMMITTEE:
* Chair – Raja Seethala, USA
* Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* Albina Altemani, Brazil
* Robert L Ferris, USA
* Isabel Fonseca, Portugal
* Douglas Gnepp, USA
* Patrick Ha, USA
* Toshitaka Nagao, Japan
* Alena Skalova, Czech Republic
* Göran Stenman, Sweden
ISBN: 978-1-925687-21-7
Article Size: 1.3 MB
 
Seethala RR, Altemani A, Ferris RL, Fonseca I, Gnepp DR, Ha P, Nagao T, Skalova A, Stenman G, Thompson LDR.
Arch Pathol Lab Med. 2019 May;143(5):578-586. doi: 10.5858/arpa.2018-0422-SA.
PubMed ID: 30500293
Article Size: 3.4 MB

Carcinomas of the Nasal Cavity and Paranasal Sinuses (TNM8)

Head & Neck, Staging
Franchi A, Bishop JA, Coleman H, Flucke U, Licitra L, Llorente JL, Stelow E, Toner M, Weinreb I, Thompson LDR.
(2018) Carcinomas of the Nasal Cavity and Paranasal Sinuses, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-20-0

SCOPE:

The dataset has been developed for the reporting of resection and biopsy specimens of mucosal malignancies originating in the nasal cavities and paranasal sinuses. Neuroectodermal neoplasms (including melanoma) and sarcomas are not included. Bone, soft tissue and lymphoma protocols are separately listed. Neck dissections and nodal excisions are dealt with in a separate dataset, and this dataset should be used in conjunction, where applicable. For additional independent tumours, complete a separate dataset for each.

EXPERT COMMITTEE:
* Chair – Alessandro Franchi, Italy
* Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* Justin Bishop, USA
* Hedley Coleman, Australia
* Uta Flucke, Netherlands
* Lisa Licitra, Italy
* José L Llorente, Spain
* Edward Stelow, USA
* Mary Toner, UK
* Ilan Weinreb, Canada
ISBN: 978-1-925687-20-0
Article Size: 1.3 MB
 
Franchi A, Bishop JA, Coleman H, Flucke U, Licitra LF, Pendás JLL, Stelow EB, Toner M, Weinreb I, Wenig BM, Thompson LDR.
Arch Pathol Lab Med. 2019 Apr;143(4):424-431. doi: 10.5858/arpa.2018-0404-SA. Epub 2018 Nov 30
PubMed ID: 30500298
Article Size: 2 MB

Carcinomas of the Nasopharynx and Oropharynx (TNM8)

Head & Neck, Oropharynx, Staging
Lewis JS Jr, Adelstein DJ, Agaimy A, Diane Carlson D, Faquin WC, Helliwell T, Hille J, Nicholls JM, Ng T, O’Sullivan B, Thompson LDR.
(2018) Carcinomas of the Nasopharynx and Oropharynx, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-18-7

SCOPE:

The dataset has been developed for the reporting of resection and biopsy specimens of the nasopharynx and oropharynx. The protocol applies to all invasive carcinomas of the nasopharynx and oropharynx including the base of tongue, tonsils, soft palate, posterior wall, and uvula. Lymphomas and sarcomas are not included. Neck dissections and nodal excisions are dealt with in a separate dataset, and this dataset should be used in conjunction, where applicable.

EXPERT COMMITTEE:
* Chair – James S Lewis Jr, USA
* Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* David Adelstein, USA
* Abbas Agaimy, Germany
* Diane Carlson, USA
* William Faquin, USA
* Tim Helliwell, UK
* Jos Hille, South Africa
* John Nicholls, Hong Kong
* Tony Ng, Canada
* Brian O’Sullivan, Canada
ISBN: 978-1-925687-18-7
Article Size: 1.5 MB
 
Lewis JS Jr, Adelstein DJ, Agaimy A, Diane Carlson D, Faquin WC, Helliwell T, Hille J, Nicholls JM, Ng T, O’Sullivan B, Thompson LDR.
Arch Pathol Lab Med. 2019 Apr;143(4):447-451. doi: 10.5858/arpa.2018-0405-SA. Epub 2018 Nov 30.
PubMed ID: 30500294
Article Size: 2 MB

Carcinomas of the Oral Cavity (TNM8)

Head & Neck, Staging
Müller S, Boy S, Day TA, Magliocca K, Richardson MS, Sloan P, Tilakaratne WM, Zain RB, Thompson LDR.
(2018) Carcinomas of the Oral Cavity, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-19-4

SCOPE:

The dataset has been developed for the reporting of resection and biopsy specimens of invasive carcinomas of the oral cavity, including lip and tongue. Mucosal melanoma, lymphomas and sarcomas are not included. In addition, neck dissections and nodal excisions are dealt with in a separate dataset, and this dataset should be used in conjunction, where applicable.

EXPERT COMMITTEE:
* Chair – Susan Müller, USA
* Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* Sonja Boy, South Africa
* Terrance Day, USA
* Kelly Magliocca, USA
* Mary Richardson, USA
* Philip Sloan, UK
* WM Tilakaratne, Sri Lanka
* Rosnah B Zain, USA
ISBN: 978-1-925687-19-4
Article Size: 1.6 MB
 
Müller S, Boy S, Day TA, Magliocca K, Richardson MS, Sloan P, Tilakaratne WM, Zain RB, Thompson LDR.
Arch Pathol Lab Med. 2019 Apr;143(4):439-446. doi: 10.5858/arpa.2018-0411-SA. Epub 2018 Nov 30.
PubMed ID: 30500296
Article Size: 3.3 MB

Ear and Temporal Bone Tumours (TNM8)

Head & Neck, Staging
Thompson LDR, Gupta R, Sandison A, Wenig BM.
(2018) Ear and Temporal Bone Tumours, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-22-4

SCOPE:

The dataset has been developed for the reporting of resection and biopsy specimens of the ear and temporal bone. It includes ONLY primary tumours of the external auditory canal, middle and inner ear, including both benign and malignant entities (specifically due to anatomic confines and management alternatives which may require significant, destructive or disfiguring surgery).

By definition, all malignancies of the external ear (pinna, concha, scaphoid, lobe, etc., such as squamous cell carcinoma, basal cell carcinoma, atypical fibroxanthoma, Merkel cell carcinoma and melanoma) are separately covered by the dermatopathology datasets.

Neck dissections and nodal excisions are dealt with in a separate dataset, and this dataset should be used in conjunction, where applicable. For bilateral tumours, a separate dataset should be completed for each tumour.

EXPERT COMMITTEE:
* Chair and Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* Ruta Gupta, Australia
* Ann Sandison, UK
* Bruce Wenig, USA
ISBN: 978-1-925687-22-4
Article Size: 1.4 MB
 
Gupta R, Sandison A, Wenig BM, Thompson LDR.
Arch Pathol Lab Med. 2019 May;143(5):593 602. doi: 10.5858/arpa.2018-0415-SA.
PubMed ID: 30500288
Article Size: 4.7 MB

Malignant Odontogenic Tumours (TNM8)

Head & Neck, Staging
Odell E, Baumhoer D, Carlos R, Hunter KD, Mosqueda-Taylor A, Richardson M, Slater L, Slootweg PJ, Speight P, Wright J, Thompson LDR.
(2018) Malignant Odontogenic Tumours, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-23-1

SCOPE:

The dataset has been developed for the reporting of biopsy and resection specimens for malignant primary odontogenic tumours. Malignant neoplasms arising in the nasal cavity and paranasal sinuses, oral cavity, salivary glands, trachea, pharynx and larynx are dealt with in separate datasets. Bone, soft tissue and lymphoma protocols will be separately listed. In addition, neck dissections and nodal excisions are dealt with in a separate dataset, and this dataset should be used in conjunction, where applicable.

EXPERT COMMITTEE:
* Chair – Edward Odell, UK
* Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* Daniel Baumhoer, Switzerland
* Roman Carlos, Guatemala
* Keith Hunter, UK
* Adalberto Mosqueda-Taylor, Mexico
* Mary Richardson, USA
* Lee Slater, USA
* Pieter Slootweg, Netherlands
* Paul Speight, UK
* John Wright, USA
ISBN: 978-1-925687-23-1
Article Size: 1.3 MB
 
Slootweg PJ, Odell EW, Baumhoer D, Carlos R, Hunter KD, Taylor AM, Richardson MS, Slater L, Speight PM, Wright J, Thompson LDR.
Arch Pathol Lab Med. 2019 May;143(5):587-592. doi: 10.5858/arpa.2018-0417-SA.
PubMed ID: 30500289
Article Size: 2.9 MB

Mucosal Melanomas of the Head and Neck (TNM8)

Head & Neck, Staging
Thompson LDR, Franchi A, Helliwell T, Müller S, Williams MD.
(2018) Mucosal Melanomas of the Head and Neck, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-25-5

SCOPE:

The dataset has been developed for the reporting of resection and biopsy specimens of mucosal melanoma arising in the nasopharynx, oropharynx, larynx, hypopharynx, oral cavity, nasal cavity and paranasal sinuses. All other malignancies and tumour categories are dealt with in separate datasets, specifically cutaneous melanoma is separately reported. Direct extension of a cutaneous primary into a mucosal site should be excluded, and would not be reported in this dataset. Metastasis to a head and neck mucosal site is also excluded. Neck dissections and nodal excisions are dealt with in a separate dataset, and this dataset should be used in conjunction, where applicable.

EXPERT COMMITTEE:
* Chair and Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* Alessandro Franchi, Italy
* Tim Helliwell, UK
* Susan Müller, USA
* Michelle Williams, USA
ISBN: 978-1-925687-25-5
Article Size: 1.2 MB
 
Williams MD, Franchi A, Helliwell T, Müller S, Thompson LDR.
Arch Pathol Lab Med. 2019 May;143(5):603-609 doi: 10.5858/arpa.2018-0412-SA.
PubMed ID: 30500297
Article Size: 4.8 MB

Nodal Excisions and Neck Dissection Specimens for Head & Neck Tumours (TNM8)

Head & Neck, Staging
Bullock M, Beitler JJ, Carlson DL, Fonseca I, Hunt J, Katabi N, Sloan P, Taylor SM, Williams MD, Thompson LDR.
(2018) Nodal Excisions and Neck Dissection Specimens for Head & Neck Tumours, Histopathology Reporting Guide, 1st Edition. International Collaboration on Cancer Reporting; Sydney, Australia. ISBN: 978-1-925687-24-8

SCOPE:

The dataset has been developed for the reporting of lymph node resections from patients with carcinomas and melanomas of the head and neck. This excludes nodal resections for lymphoma and sarcomas. It is not intended for use in reporting lymph node core biopsy or fine needle aspirations. Carcinomas covered by the dataset include squamous cell carcinomas, sinonasal carcinomas, salivary and non-salivary type adenocarcinomas and neuroendocrine tumours. Pathologists may also apply the dataset to metastatic non-Merkel cutaneous squamous cell carcinomas and other cutaneous carcinomas. This dataset is to be used in conjunction with other datasets in the Head and Neck Series.

EXPERT COMMITTEE:
* Chair – Martin Bullock, Canada
* Series Champion – Lester Thompson, USA
DOMAIN EXPERTS:
* Jonathan Beitler, USA
* Diane L. Carlson, USA
* Isabel Fonseca, Portugal
* Jennifer Hunt, USA
* Nora Katabi, USA
* Philip Sloan, UK
* S. Mark Taylor, Canada
* Michelle Williams, USA
ISBN: 978-1-925687-24-8
Article Size: 2 MB
 
Bullock M, Beitler JJ, Carlson DL, Fonseca I, Hunt J, Katabi N, Sloan P, Taylor SM, Williams MD, Thompson LDR.
Arch Pathol Lab Med. 2019 Apr;143(4):452-462. doi: 10.5858/arpa.2018-0421-SA. Epub 2018 Nov 30.
PubMed ID: 30500291
Article Size: 4.8 MB

HN-CLEAR: Head and Neck Consensus Language for Ease and Reproducibility, a Multidisciplinary Consensus Mechanism for Head and Neck Pathology

Head & Neck, Staging
Gupta R, Bal M, Bishop JA, Hunter KD, Magliocca K, Seethala RR, Thompson LDR, Weinreb I, Angelos P, Beadle B, Bell RB, Clark JR, Ferris R, Huang SH, Hayes DN, Ladwa R, Yang J, Cipriani NA, Nelson BL, Sadow PM, Lewis JS.
Head Neck Pathol. 2023 Sep;17(3):877-880. doi: 10.1007/s12105-023-01570-w.
Background (first paragraph) only: The head and neck region harbors a diverse range of tissue types and pathologies in close anatomical proximity. It also includes some of the most common human malignancies such as squamous cell carcinoma of the skin and aerodigestive tract while also including infections, inflammatory disorders, and many rare entities such as salivary gland and odontogenic neoplasms. The head and neck brings together pathologists with diverse training and sub-specialty backgrounds including head and neck, maxillofacial, endocrine pathology, dermatopathology, cytopathology, and other subspecialists as well as general surgical pathologists. The broad range of diagnostic terminologies and prognostic issues that influence patient management in head and neck pathology are further confounded by overlapping and confusing terminology and lack of robust evidence in many areas. Uniform and evidence-based diagnostic and prognostic terminologies are needed to inform the treatment of patients and support the design of clinical trials, epidemiological and fundamental research, cancer registries for education and preventive strategies, and assist policy makers in the allocation of health care resources.
PubMed ID: 37486534
Article Size: <1 MB