Ear Nose Throat J. 2021 Sep;100(5_suppl):533S-535S. doi: 10.1177/0145561319890162.
FIRST PARAGRAPH: Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a recently recognized indolent neoplasm separated from invasive follicular variant of papillary thyroid carcinoma (FVPTC). NIFTP is a noninvasive, partially to completely encapsulated thyroid follicular neoplasm arranged in almost exclusively follicular architecture, showing papillary carcinoma-like nuclear features in an adequately sampled tumor. In order to qualify for placement in this category, several inclusion and exclusion criteria must be met. Importantly, there can be no invasion at the tumor periphery (ie, usually the capsule) that has been completely sampled for histologic review. There cannot be another recognized pattern of papillary carcinoma, and no more than 30% of the tumor should be solid, trabecular, or insular. There cannot be any tumor necrosis and no increased mitoses of _4 mitoses/2 mm2. Finally, there cannot be any true papillary structures.
PubMed ID: 31760798
Article Size: <1 MB